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Schizoaffective

Schizoaffective disorder is one of the most confusing and controversial diagnostic categories in psychiatry. People suffering from schizoaffective disorder experience a chronic roller-coaster ride of symptoms and problems that may be more difficult to cope with than either of its parent diseases, schizophrenia or affective disorders (formerly known as mood disorders).

Researchers have identified two subtypes of schizoaffective disorder: bipolar type and depressive type. Bipolar type is associated with the presence of manic or mixed episodes. Such episodes bring on sudden elation, euphoria, or extreme irritability to the point of serious impairment. Depressive type is associated with major depressive episodes. Depressive episodes are often characterized by feelings of worthlessness, hopelessness or indifference, and inability to concentrate or remember details, and thoughts of death or suicide attempts.

Like schizophrenia and affective disorders, schizoaffective disorder is caused by a chemical imbalance in the brain's neurotransmitters.

Since schizoaffective disorder bears a close resemblance to both schizophrenia and affective disorders, people with the illness experience a combination of symptoms associated with both diseases. To be diagnosed with schizoaffective disorder a person must not meet the criteria for either schizophrenia or affective disorder. However, a person must have at one time experienced both a schizophrenic and a mood disturbance and, at another time, experienced psychotic symptoms without affective symptoms. These symptoms include:

Psychotic Symptoms

  • Delusions
  • Hallucinations
  • Disorganized thinking
  • Agitation
  • Lack of drive or initiative
  • Social withdrawal
  • Apathy

Affective Symptoms

  • Extreme mood swings from mania to depression
  • Hyperactivity
  • Thoughts of death or suicide
  • Decreased need for sleep
  • Acute psychosis
  • Loss of appetite

Like schizophrenia, schizoaffective disorder usually begins in early adulthood. Although research on the disorder is scarce, women seem to suffer from the illness more often than men.

Schizoaffective disorder responds to treatment with antimanics (such as lithium), antidepressants, and antipsychotics.

Janssen, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. This page was last updated on: Oct 03 2007 at 14:51:16 EDT